CBD is a cannabinoid, a type of substance found naturally in cannabis (marijuana and hemp) plants. CBD does not produce the “high” sensation that many people associate with cannabis. Tetrahydrocannabinol (THC), a distinct form of cannabinoid, is responsible for this sensation.
To control their symptoms, some persons with chronic pain utilise topical CBD products, particularly CBD oil. CBD oil may help you to:
CBD products and pain management have been the subject of promising study.
CBD may be a viable alternative for patients who suffer from chronic pain and rely on drugs like opioids, which can be addictive and have several adverse effects. More research is needed, however, to confirm CBD oil’s and other products’ pain-relieving properties.
Epidiolex, an epilepsy medicine, is the only CBD product on the market that has been approved by the Food and Drug Administration (FDA).
There are no nonprescription CBD products that have been authorised by the FDA. They aren’t subject to the same purity and dose restrictions as other drugs.
Continue reading to learn more about CBD’s possible pain-relieving properties. You can also discuss it with your doctor to determine if it’s a viable choice for you.
CBD Oil for Chronic Pain
The endocannabinoid system is a cell-signaling system found in everyone (ECS).
CBD, according to some researchers, interacts with endocannabinoid receptors in the brain and immune system, which are a key component of the ECS.
Receptors are little proteins found on the surface of your cells. They receive chemical messages from various stimuli and assist your cells in responding.
This reaction has anti-inflammatory and pain-relieving properties, which aid in pain management. This suggests that CBD oil and other CBD-based treatments may help those who suffer from chronic pain, such as chronic back pain.
A 2018 study looked at how effective CBD is at treating chronic pain. The review looked at trials that took place between 1975 and March of this year. Various types of pain were investigated in these research, including:
Researchers determined that CBD was effective in overall pain treatment and had no harmful side effects based on these investigations.
CBD can help with arthritic pain alleviation.
According to a 2016 study
The usage of CBD in rats with arthritis was studied by Trusted Source.
CBD gel was applied to rats for four days in a row. Each day, the rats were given 0.6, 3.1, 6.2, or 62.3 milligrammes (mg). The rats’ damaged joints showed less inflammation and pain, according to the researchers. There were no noticeable negative consequences.
The pain scores of rats given low dosages of 0.6 or 3.1 mg did not improve. The researchers discovered that 6.2 mg/day was an effective amount for reducing discomfort and edoema in rats.
Furthermore, animals receiving 62.3 mg/day showed similar results to rats receiving 6.2 mg/day. They did not experience less pain after receiving a significantly higher amount.
CBD gel’s anti-inflammatory and pain-relieving properties could aid those with arthritis. More human research, on the other hand, are required.
CBD can help in cancer treatment.
CBD is also used by some cancer patients. CBD has been demonstrated in studies on mice to help reduce malignant tumours. The majority of human studies, on the other hand, have looked into the effect of CBD in reducing pain associated with cancer and cancer therapy.
CBD has been suggested by the National Cancer Institute (NCI) as a feasible solution for minimising chemotherapy adverse effects such as:
discomfort, vomiting, and a loss of appetite
Research participants received oral sprays of a THC-CBD compound in a 2010 study on cancer-related pain. Opioids were administered in conjunction with the THC-CBD extract. The extract provided more effective pain alleviation than the opioids alone, according to one study.
A similar conclusion was reported in a 2013 study on THC and THC-CBD oral sprays. Many of the same researchers that worked on the 2010 study contributed to this one. More proof is still required.
Migraine treatment with CBD
There are few studies on CBD and migraines. CBD is also studied when it is combined with THC, rather than when it is used alone, according to the present research.
According to the findings of a 2017 study, CBD and THC can help migraine sufferers experience less acute and intense pain.
Some participants in this two-phase trial were given a mixture of two drugs. One of the compounds had 9% CBD and almost no THC. THC was present in the other molecule in a concentration of 19%. Oral dosing was used.
When the doses were less than 100 mg, there was no effect on pain in phase I. Acute pain was reduced by 55% when the doses were increased to 200 mg.
In phase II, participants who received a mixture of CBD and THC chemicals experienced a 40.4 percent reduction in migraine attacks. The dosage was 200 milligrammes per day.
The combination of chemicals was somewhat more effective than 25 mg of tricyclic antidepressant amitriptyline. In the trial, amitriptyline reduced migraine attacks by 40.1 percent.
Cluster headaches were also relieved by the combination of CBD and THC chemicals, but only if the participants had a history of migraines as a child.
CBD’s negative consequences
CBD has no known side effects, and most topical CBD preparations do not enter the bloodstream.
However, there are some probable negative effects, such as:
alterations in appetite
alterations in weight
CBD may interact with the following substances:
prescription pharmaceuticals nutritional supplements some over-the-counter (OTC) drugs
If any of your drugs or supplements have a “grapefruit warning,” proceed with caution. Both grapefruit and CBD interfere with enzymes involved in medication metabolism.
CBD, like other medications and supplements, has the potential to cause liver damage.
CBD-rich cannabis extract raised the risk of liver damage in mice, according to one study. Some of the mice, on the other hand, had been force-fed extremely huge amounts of CBD-rich cannabis extract.
While there isn’t enough evidence to support CBD or CBD oil as a preferred way of pain relief, researchers agree that these products have a lot of promise.
CBD products may be able to provide comfort for many people suffering from chronic pain without creating intoxication or addiction.
Consult your doctor if you’re interested in trying CBD for chronic pain. They can assist you in determining an appropriate starting dosage.
Here’s where you can learn more about CBD dose.
Is CBD a legal substance? CBD products made from hemp (with less than 0.3 percent THC) are legal in the United States, however they are still banned in several states. CBD products produced from marijuana are prohibited on the federal level, although they are lawful in several states. Check the laws of your home state as well as the laws of any country you visit. It’s important to remember that nonprescription CBD products aren’t FDA-approved and may be mislabeled.